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Understanding Our Endocannabinoid System

Understanding Our Endocannabinoid System

In order to understand how CBD helps with numerous biological processes, one must understand the endocannabinoid system (ECS). The ECS is involved in the regulation of a broad array of physiological and biochemical systems, including neurological, gastrointestinal, inflammation (pain), behavioral, and sleep. The ECS, only recently discovered, may indeed be the most important biological system involved in maintaining homeostasis, or equilibrium, throughout the body.

The ECS is comprised of two main receptors, cannabinoid 1 (CB1) and cannabinoid 2 (CB2). CB1 receptors are mainly found in the brain and central nervous system, while CB2 receptors are predominantly found in peripheral organs involved with the immune system. Your body produces endocannabinoids such as anandamide and 2-AG, which are thought to be natural regulators of the ECS.

Indeed, Endocannabinoid Deficiency Syndrome (EDS) includes a variety of afflictions (fibromyalgia, irritable bowel syndrome, migraines, etc.) thought to be due to low levels of the body’s endocannabinoids. By adding phytocannabinoids such as CBD, many of these devastating symptoms can be decreased, as the phytocannabinoids (plant-derived) mimic the endocannabinoids (body-derived) by modulating the ECS.

Full-spectrum CBD oil is a rich extract made from the flowers and leaves of the hemp plant. The oil is rich in nutrients such as omega-3 and omega-6 fatty acids, vitamins, terpenes, and amino acids. Enriched with high CBD content, CBD oil also contains at least 85 other phytocannabinoids. Some of these additional cannabinoids also show promising health benefits, such as cannabinol (CBN), cannabigerol (CBG), and cannabichromene (CBC). In fact, it has been shown that CBD oil is more therapeutic than CBD isolate alone. It is thought that the mixture of cannabinoids act synergistically, also known as the “entourage effect”.

Our CBD tinctures contain full-spectrum CBD oil mixed with medium–chain triglyceride oil (which helps with the absorption of CBD) and black cumin seed oil (antioxidant-rich). Some specific tinctures may also contain therapeutic-grade essential oils, which assist with the therapeutic benefits of CBD and are formulated to treat specific symptoms.

As mentioned above, the ECS is critical in maintaining homeostasis, defined as “the tendency towards a relatively stable equilibrium between independent elements of the human body”. CBD and other phytocannabinoids directly interact with the ECS, which is evident in the various and numerous health benefits:

Acne Addiction ADD/ADHD ALS
Alzheimer’s Anorexia Anxiety Cancer
Celiac Disease Crohn’s Depression Diabetes
Fibromyalgia IBS Inflammation Insomnia
Migraines Nausea OCD Osteoporosis
Pain Parkinson’s PTSD Stress
Rhuematoid Arthritis Spasticity Weight Loss
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Label Accuracy of CBD Products: Understanding True Content

26% Of Tested Products Contained Less CBD Than Labeled.

Due to discrepancies in federal and state cannabis laws, there is little regulation and inadequate oversight concerning the labeling of CBD products. In fact, the US Food and Drug Administration recently found that 26% of tested products contained less CBD than labeled. In addition, some companies list their content of CBD misleadingly as the weight of hemp-extracted CBD oil instead of the actual weight of CBD.

What Is CBD?

In order to understand the difference, it is critical to understand the content of hemp-extracted oil. Full-spectrum hemp oil is a viscous liquid that is rich in phytocannabinoids, as well as other naturally occurring components. These include:

  • Vitamins (e.g., vitamins B1, B2, B3, B6 and E)
  • Amino Acids (e.g., glutamic acid and arginine)
  • Carbohydrates (e.g., rich in fiber) – Fatty Acids (e.g., omega-3 and omega-6 fatty acids)
  • Trace Minerals (e.g., calcium, iron, magnesium, zinc)

Of the phytocannabinoids rich in hemp, the most abundant are CBD, CBG, CBN, and CBC. In addition, there are numerous other phytocannabinoids present at low levels. It is suggested that the entire profile makeup of the cannabinoids work together to affect various biological processes, described as the entourage effect.

How Much CBD Is In The Bottle?

Depending on the strain of the hemp plant, the CBD content of hemp-extracted oil may range from 5-60%. To determine the true CBD content, it is crucial to perform third-party and state-regulated testing on manufactured CBD products.

Knowing the content of CBD oil, is NOT the same as the weight of CBD in a product. A bottle of CBD tincture labeled 500 mg CBD oil can not be determined by the weight of CBD oil. When CBD oil analyzed contains 25% CBD, the tincture label should read 125 mg CBD. This is very important when choosing your optimal and correct dosage.

At MJ BioEssentials, the hemp-extracted CBD oils used in our products have been 3rd party tested by certified and state-regulated analytical laboratories, which generates a phytocannabinoid profile of the extract. This enables accurate and reproducible measurement of the TRUE CBD content of our complete line of CBD products.

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8 Amazing Ways CBD Can Improve Your Pets Health

8 Amazing ways CBD can Improve your pets health

  1. Reduces inflammation (decreases arthritic and nerve-related pain)
  2. Decreases anxiety (separation, loud noises, inclement weather)
  3. Reduces gastrointestinal inflammation (help with irritable bowel disease)
  4. Protects from oxidative stress (antioxidant properties)
  5. Provides antibiotic properties
  6. Helps prevent allergies, hypersensitive and immune diseases
  7. Helps to prevent muscle spasms or seizures
  8. Reduces skin inflammation (atopic dermatitis)

Does your pet suffer from:

  • Separation Anxiety – Loud Noises (Thunder, Fireworks)
  • Loss of Mobility
  • Arthritic Pain
  • Nausea
  • Insomnia
  • Gastrointestinal Issues
  • Low Energy

Endocannabinoid system

CBD has the ability to stimulate your pet’s endocannabinoid system (ECS). MJ BioEssentials CBD-PetEssentials products will help your loving companion!he same way as in humans: by promoting overall well-being and physiologic homeostasis. Our products are a natural and effective alternative to veterinary pharmaceuticals, which can cause numerous and dangerous adverse side-effects (e.g., damage to liver, kidney, and GI tract). CBD-PetEssentials products are non-psychoactive, safe (no known side-effects or lethal dose), and easy to ingest. In addition, the cost is much less than pharmaceuticals.

8 Amazing ways CBD can Improve your pets health

How do I give CBD-PetEssentials to my pet?

Our CBD-PetEssentials tinctures can be given under the tongue (sublingual) or by adding it to your pets food or favorite treat. Our tinctures are safe and effective, with no known side-effects or risk of overdosing. Simple use our CBD-PetEssentials dosing chart to find a  starting dose for your pet. Slowly increase as needed to find the optimal dose for your pet!


PetEssentials dosing chart will help to find the correct starting dose for your pet. Slowly increase as needed to find the optimal dose for your pet!

Pet Weight (lbs) Low DosageA (mg) Medium DosageA (mg) High DosageA (mg)
10 1 2 5
20 2 4 10
30 3 6 15
40 4 8 20
50 5 10 25
60 6 12 30
70 7 14 35
80 8 16 40
90 9 18 45
100* 10 20 50

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. By using this site you agree to follow the Privacy Policy and all Terms & Conditions printed on this site. Void Where Prohibited By Law.